| 1 |
Leon LR, Bouchama A. Heat stroke[J]. Compr Physiol, 2015, 5 (2): 611-647.
|
| 2 |
Lim CL. Heat sepsis precedes heat toxicity in the pathophysiology of heat stroke-a new paradigm on an ancient disease[J]. Antioxidants (Basel), 2018, 7 (11): 149.
|
| 3 |
Centers for Disease Control and Prevention (CDC). Heat-related deaths--United States, 1999-2003[J]. MMWR Morb Mortal Wkly Rep, 2006, 55 (29): 796-798.
|
| 4 |
Booth JN, 3rd, Davis GG, Waterbor J, et al. Hyperthermia deaths among children in parked vehicles: an analysis of 231 fatalities in the United States, 1999-2007[J]. Forensic Sci Med Pathol, 2010, 6 (2): 99-105.
|
| 5 |
Fatima Siddiqui G, Vir Singh M, Shrivastava A, et al. Children left unattended in parked vehicles in India: an analysis of 40 fatalities from 2011 to 2020[J]. J Trop Pediatr, 2021, 67 (3): fmaa075.
|
| 6 |
Hosokawa Y, Adams WM, Belval LN, et al. Exertional heat illness incidence and on-site medical team preparedness in warm weather[J]. Int J Biometeorol, 2018, 62 (7): 1147-1153.
|
| 7 |
O'Connor FG, Heled Y, Deuster PA. Exertional heat stroke, the return to play decision, and the role of heat tolerance testing: a clinician's dilemma[J]. Curr Sports Med Rep, 2018, 17 (7): 244-248.
|
| 8 |
Al Mahri S, Bouchama A. Heatstroke[J]. Handb Clin Neurol, 2018 (157): 531-545.
|
| 9 |
Gostimirovic M, Novakovic R, Rajkovic J, et al. The influence of climate change on human cardiovascular function[J]. Arch Environ Occup Health, 2020, 75 (7): 406-414.
|
| 10 |
Roberts GT, Ghebeh H, Chishti MA, et al. Micro-vascular injury, thrombosis, inflammation, and apoptosis in the pathogenesis of heat stroke: a study in baboon model[J]. Arterioscler Thromb Vasc Biol, 2008, 28 (6): 1130-1136.
|
| 11 |
Knapik JJ, Epstein Y. Exertional heat stroke: pathophysiology, epidemiology, diagnosis, treatment, and prevention[J]. J Spec Oper Med, 2019, 19 (2): 108-116.
|
| 12 |
Kataoka H, Ushiyama A, Akimoto Y, et al. Structural behavior of the endothelial glycocalyx is associated with pathophysiologic status in septic mice: an integrated approach to analyzing the behavior and function of the glycocalyx using both electron and fluorescence intravital microscopy[J]. Anesth Analg, 2017, 125 (3): 874-883.
|
| 13 |
李莉，古正涛，刘志锋，等. Caspase-3在热打击诱导人脐静脉内皮细胞凋亡中的作用[J].实用医学杂志，2014，30（6）：871-874.
|
| 14 |
Li L, Tan H, Gu Z, et al. Heat stress induces apoptosis through a Ca2+-mediated mitochondrial apoptotic pathway in human umbilical vein endothelial cells[J]. PLoS One, 2014, 9 (12): e111083.
|
| 15 |
Gu ZT, Li L, Wu F, et al. Heat stress induced apoptosis is triggered by transcription-independent p53, Ca2+ dyshomeostasis and the subsequent bax mitochondrial translocation[J]. Sci Rep, 2015 (5): 11497.
|
| 16 |
Xiao G, Yuan F, Geng Y, et al. Eicosapentaenoic acid enhances heatstroke-impaired intestinal epithelial barrier function in rats[J]. Shock, 2015, 44 (4): 348-356.
|
| 17 |
童华生，段鹏凯，旋学智，等.肠系膜淋巴管结扎对重症中暑大鼠凝血功能的影响[J].解放军医学杂志，2016，41（2）：94-96.
|
| 18 |
Zhang C, Zhao XH, Yang L, et al. Resveratrol alleviates heat stress-induced impairment of intestinal morphology, microfora, and barrier integrity in broilers[J]. Poult Sci, 2017, 96 (12): 4325-4332.
|
| 19 |
Slimen IB, Najar T, Ghram A, et al. Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review [J]. Int J Hyperthermia, 2014, 30 (7): 513-523.
|
| 20 |
Pradelli LA, Bénéteau M, Ricci JE. Mitochondrial control of caspase-dependent and -independent cell death[J]. Cell Mol Life Sci, 2010, 67 (10): 1589-1597.
|
| 21 |
Wang G, Shen T, Li P, et al. The increase in IL-1β in the early stage of heatstroke might be caused by splenic lymphocyte pyroptosis induced by mtROS-mediated activation of the NLRP3 inflammasome[J]. Front Immunol. 2019 (10): 2862.
|
| 22 |
Pei Y, Geng Y, Su L. Pyroptosis of HUVECs can be induced by heat stroke[J]. Biochem Biophys Res Commun, 2018, 506 (3): 626-631.
|
| 23 |
Guyton AC, Hall JE. Body temperature, temperature regulation, and fever[M]// Schmitt W, Gruliow R. Textbook of medical physiology. 11th ed. Pennsylvania: Elsevier, 2006: 1-1152.
|
| 24 |
Mei C, He SS, Yin P, et al. Magnolol pretreatment attenuates heat stress-induced IEC-6 cell injury[J]. J Zhejiang Univ Sci B, 2016, 17 (6): 413-424.
|
| 25 |
Liu F, Cottrell JJ, Furness JB, et al. Selenium and vitamin E together improve intestinal epithelial barrier function and alleviate oxidative stress in heat-stressed pigs[J]. Exp Physiol, 2016, 101 (7): 801-810.
|
| 26 |
Li L, Tan H, Zou Z, et al. Preventing necroptosis by scavenging ROS production alleviates heat stress-induced intestinal injury[J]. Int J Hyperthermia, 2020, 37 (1): 517-530.
|
| 27 |
Lin YF, Liu TT, Hu CH, et al. Expressions of chemokines and their receptors in the brain after heat stroke-induced cortical damage[J]. J Neuroimmunol, 2018 (318): 15-20.
|
| 28 |
Bouchama A, Ollivier V, Roberts G, et al. Experimental heatstroke in baboon: analysis of the systemic inflammatory response[J]. Shock, 2005, 24 (4): 332-335.
|
| 29 |
Leon LR, Blaha MD, DuBose DA. Time course of cytokine, corticoste rone, and tissue injury responses in mice during heat strain recovery[J]. J Appl Physiol (1985), 2006, 100 (4): 1400-1409.
|
| 30 |
Sonna LA, Wenger CB, Flinn S, et al. Exertional heat injury and gene expression changes: a DNA microarray analysis study[J]. J Appl Physiol (1985), 2004, 96 (5): 1943-1953.
|
| 31 |
Hammami MM, Bouchama A, Al-Sedairy S, et al. Concentrations of soluble tumor necrosis factor and interleukin-6 receptors in heatstroke and heatstress[J]. Crit Care Med, 1997, 25 (8): 1314-1319.
|
| 32 |
Hu J, Kang HJ, Liu C, et al. Response of regulatory T cells to classic heat stroke in mice[J]. Exp Ther Med, 2018, 16 (6): 4609-4615.
|
| 33 |
Dehbi M, Baturcam E, Eldali A, et al. Hsp-72, a candidate prognostic indicator of heatstroke[J]. Cell Stress Chaperones, 2010, 15 (5): 593-603.
|
| 34 |
Rani M, Nicholson SE, Zhang Q, et al. Damage-associated molecular patterns (DAMPs) released after burn are associated with inflammation and monocyte activation[J]. Burns, 2017, 43 (2): 297-303.
|
| 35 |
Huisse MG, Pease S, Hurtado-Nedelec M, et al. Leukocyte activation: the link between inflammation and coagulation during heatstroke. A study of patients during the 2003 heat wave in Paris[J]. Crit Care Med, 2008, 36 (8): 2288-2295.
|
| 36 |
Niu B, Zhang T, Hu H, et al. Transcriptome sequencing reveals astrocytes as a therapeutic target in heat-stroke[J]. Neurosci Bull, 2017, 33 (6): 627-640.
|
| 37 |
Mittal R, Coopersmith CM. Redefining the gut as the motor of critical illness[J]. Trends Mol Med, 2014, 20 (4): 214-223.
|
| 38 |
Dehbi M, Uzzaman T, Baturcam E, et al. Toll-like receptor 4 and high-mobility group box 1 are critical mediators of tissue injury and survival in a mouse model for heatstroke[J]. PLoS One, 2012, 7 (9): e44100.
|
| 39 |
Huang W, Xie W, Gong J, et al. Heat stress induces RIP1/RIP3-dependent necroptosis through the MAPK, NF-κB, and c-Jun signaling pathways in pulmonary vascular endothelial cells[J]. Biochem Biophys Res Commun, 2020, 528 (1): 206-212.
|
| 40 |
Liu Y, Zhou G, Wang Z, et al. NF-κB signaling is essential for resistance to heat stress-induced early stage apoptosis in human umbilical vein endothelial cells[J]. Sci Rep, 2015 (5): 13547.
|
| 41 |
Heeba GH, El-Hanafy AA. Nebivolol regulates eNOS and iNOS expressions and alleviates oxidative stress in cerebral ischemia/reperfusion injury in rats[J]. Life Sci, 2012, 90 (11-12): 388-395.
|
| 42 |
Tong H, Tang Y, Chen Y, et al. HMGB1 activity inhibition alleviating liver injury in heatstroke[J]. J Trauma Acute Care Surg, 2013, 74 (3): 801-807.
|
| 43 |
Tong HS, Tang YQ, Chen Y, et al. Early elevated HMGB1 level predicting the outcome in exertional heatstroke[J]. J Trauma, 2011, 71 (4): 808-814.
|
| 44 |
Li Y, Zhu X, Zhang M, et al. Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice[J]. PeerJ, 2019 (7): e8216.
|
| 45 |
Deitch EA. Gut lymph and lymphatics: a source of factors leading to organ injury and dysfunction[J]. Ann N Y Acad Sci, 2010 (1207 Suppl 1): E103-E111.
|
| 46 |
Tong H, Chen R, Yin H, et al. Mesenteric lymph duct ligation alleviating lung injury in heatstroke[J]. Shock, 2016, 46 (6): 696-703.
|
| 47 |
Hemmelgarn C, Gannon K. Heatstroke: thermoregulation, pathophysiology, and predisposing factors[J]. Compend Contin Educ Vet, 2013, 35 (7): E4.
|
| 48 |
Wang Y, Xiao QM, Qi HN, et al. Value of APACHE Ⅱ score and DIC score in predicting the death of patients with heat stroke[J]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi, 2019, 37 (1): 43-45.
|
| 49 |
Leon LR, Helwig BG. Heat stroke: role of the systemic inflammatory response[J]. J Appl Physiol (1985), 2010, 109 (6): 1980-1988.
|
| 50 |
Zhong L, Wu M, Wang C, et al. Clinical characteristics and outcomes of patients with severe heatstroke complicated with disseminated intravascular coagulation: a case-control study[J]. Thromb Res, 2021 (197): 120-123.
|
| 51 |
Asakura H, Suga Y, Yoshida T, et al. Pathophysiology of disseminated intravascular coagulation (DIC) progresses at a different rate in tissue factor-induced and lipopolysaccharide-induced DIC models in rats[J]. Blood Coagul Fibrinolysis, 2003, 14 (3): 221-228.
|
| 52 |
Khogali M. Epidemiology of heat illnesses during the Makkah Pilgrimages in Saudi Arabia[J]. Int J Epidemiol, 1983, 12 (3): 267-273.
|
| 53 |
King MA, Leon LR, Morse DA, et al. Unique cytokine and chemokine responses to exertional heat stroke in mice[J]. J Appl Physiol (1985), 2017, 122 (2): 296-306.
|
| 54 |
刘喆滢，吉晶晶，洪欣欣，等.重症中暑临床救治方法现状与研究进展[J/CD].中华重症医学电子杂志（网络版），2019，5（2）：176-184.
|
| 55 |
李莉，刘志峰，古正涛，等.重症中暑中枢神经系统病变机制的研究进展[J].中华危重病急救医学，2013，25（9）：570-572.
|
| 56 |
Shapiro Y, Seidman DS. Field and clinical observations of exertional heat stroke patients[J]. Med Sci Sports Exerc, 1990, 22 (1): 6-14.
|
| 57 |
Patel DR, Gyamfifi R, Torres A. Exertional rhabdomyolysis and acute kidney injury[J]. Phys Sportsmed, 2009, 37 (1): 71-79.
|
| 58 |
European Association for the Study of the Liver, Clinical Practice Guidelines Panel, Wendon J, et al. EASL clinical practical guidelines on the management of acute (fulminant) liver failure[J]. J Hepatol, 2017, 66 (5): 1047-1081.
|
| 59 |
Lim CL. Heat sepsis precedes heat toxicity in the pathophysiology of heat stroke-a new paradigm on an ancient disease[J]. Antioxidants (Basel), 2018, 7 (11): e149.
|
| 60 |
Seo MJ, Hong JM, Kim SJ, et al. Genipin protects dgalactosamine and lipopolysaccharide-induced hepatic injury through suppression of the necroptosis-mediated inflammasome signaling[J]. Eur J Pharmacol, 2017 (812): 128-137.
|
| 61 |
Zhang B, Wang B, Cao S, et al. Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation [J]. Int J Mol Med, 2017, 39 (5): 1111-1118.
|
| 62 |
Chao TC, Sinniah R, Pakiam JE. Acute heat stroke deaths[J]. Pathology, 1981, 13 (1): 145-156.
|
| 63 |
Paidas CN, Mooney ML, Theodorakis NG, et al. Accelerated recovery after endotoxic challenge in heat shock-pretreated mice[J]. Am J Physiol Regul Integr Comp Physiol, 2002, 282 (5): R1374-R1381.
|
| 64 |
陈友谊，孙备.重症急性胰腺炎并胃肠道功能障碍的研究进展[J].中华胰腺病杂志，2013，13（2）：42-144.
|
| 65 |
Liu Z, Liu JH, Liu Y, et al. Proteomic analysis and identification of intestinal FBP as a predictor of gut dysfunction during heatstroke in mice[J]. J Surg Res, 2012, 173 (2): 332-340.
|
| 66 |
Wang YH, Liu TT, Kung WM, et al. Expression of aquaporins in intestine after heat stroke[J]. Int J Clin Exp Pathol, 2015, 8 (8): 8742-8753.
|
| 67 |
Hifumi T, Kondo Y, Shimizu K, et al. Heat stroke [J]. J Intensive Care, 2018 (6): 30.
|
| 68 |
Zhong L, Wu M, Liu Z, et al. Risk factors for the 90-day prognosis of severe heat stroke: a case-control study[J]. Shock, 2021, 55 (1): 61-66.
|
| 69 |
Deitch EA. Animal models of sepsis and shock: a review and lessons learned[J]. Shock, 1998, 9 (1): 1-11.
|
| 70 |
Chen SH, Lin MT, Chang CP. Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke[J]. Curr Neuropharmacol, 2013, 11 (2): 129-140.
|
| 71 |
Davis BC, Tillman H, Chung RT, et al. Heat stroke leading to acute liver injury & failure: a case series from the Acute Liver Failure Study Group[J]. Liver Int, 2017, 37 (4): 509-513.
|
| 72 |
He S, Liu F, Xu L, et al. Protective effects of ferulic acid against heat stress-induced intestinal epithelial barrier dysfunction in vitro and in vivo[J]. PLoS One, 2016, 11 (2): e0145236.
|
| 73 |
Xia Z, Huang L, Yin P, et al. L-Arginine alleviates heat stress-induced intestinal epithelial barrier damage by promoting expression of tight junction proteins via the AMPK pathway[J]. Mol Biol Rep, 2019, 46 (6): 6435-6451.
|
| 74 |
Lopetuso LR, Scaldaferri F, Bruno G, et al. The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors[J]. Eur Rev Med Pharmacol Sci, 2015, 19 (6): 1068-1076.
|
| 75 |
de la Cuesta-Zuluaga J, Mueller NT, Corrales-Agudelo V, et al. Metformin is associated with higher relative abundance of mucin-degrading Akkermansia muciniphila and several shortchain fatty acid-producing microbiota in the gut[J]. Diabetes Care, 2017, 40 (1): 54-62.
|
| 76 |
Hou Y, Wang L, Yi D, et al. Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid[J]. Br J Nutr, 2014, 111 (10): 1748-1758.
|
| 77 |
Davison G, Marchbank T, March DS, et al. Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers[J]. Am J Clin Nutr, 2016, 104 (2): 526-536.
|
| 78 |
Cao Y, Liu Z, Xiao W, et al. 4-phenylbutyrate prevents endoplasmic reticulum stress-mediated apoptosis induced by heatstroke in the intestines of mice[J]. Shock, 2020, 54 (1): 102-109.
|
| 79 |
Tang J, Sun Y, Wu WK, et al. Propofol lowers serum PF4 level and partially corrects hypercoagulopathy in endotoxemic rats[J]. Biochim Biophys Acta, 2010, 1804 (9): 1895-1901.
|
| 80 |
Lamprecht M, Bogner S, Schippinger G, et al. Probiotic supplementation affects markers of intestinal barrier, oxidation, and inflammation in trained men; a randomized, double-blinded, placebo-controlled trial[J]. J Int Soc Sports Nutr, 2012, 9 (1): 45.
|
| 81 |
Chen CM, Hou CC, Cheng KC, et al. Activated protein C therapy in a rat heat stroke model[J]. Crit Care Med, 2006, 34 (7): 1960-1966.
|
| 82 |
Vincent JL, Ramesh MK, Ernest D, et al. A randomized, double-blind, placebocontrolled, phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation[J]. Crit Care Med, 2013, 41 (9): 2069-2079.
|
| 83 |
Geng Y, Li R, He S X, et al. Dexmedetomidine attenuates acute lung injury induced by heatstroke and improve outcome[J]. Shock, 2019, 52 (5): 532-539.
|
| 84 |
Kobayashi K, Mimuro S, Sato T, et al. Dexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model[J]. J Anesth, 2018, 32 (6): 880-885.
|
| 85 |
Lin CH, Tsai CC, Chen TH, et al. Oxytocin maintains lung histological and functional integrity to confer protection in heat stroke[J]. Sci Rep, 2019, 9 (1): 18390.
|
| 86 |
Tao Z, Cheng M, Wang SC, et al. JAK2/STAT3 pathway mediating inflammatory responses in heatstroke-induced rats[J]. Int J Clin Exp Pathol, 2015, 8 (6): 6732-6739.
|
| 87 |
Zhu YH, Pei ZM. GSK2193874 treatment at heatstroke onset reduced cell apoptosis in heatstroke mice[J]. Cell Mol Biol (Noisy-le-grand), 2018, 64 (7): 36-42.
|
| 88 |
Ji J, Hong X, Su L, et al. Proteomic identification of hippocalcin and its protective role in heatstroke-induced hypothalamic injury in mice[J]. J Cell Physiol, 2019, 234 (4): 3775-3789.
|
| 89 |
Ji J, Gu Z, Li H, Su L, et al. Cryptdin-2 predicts intestinal injury during heatstroke in mice[J]. Int J Mol Med, 2018, 41 (1): 137-146.
|
| 90 |
Chang CY, Chen JY, Chen SH, et al. Therapeutic treatment with ascorbate rescues mice from heat stroke-induced death by attenuating systemic inflammatory response and hypothalamic neuronal damage[J]. Free Radic Biol Med, 2016 (93): 84-93.
|
| 91 |
Monzon B, Hegarty K, Rech MA. A knack for "NAC": treatment for heat stroke induced acute liver injury[J]. Am J Emerg Med, 2020, 38 (4): 853.e1-853.e3.
|
| 92 |
Inoue Y, Nakahara K, Maruyama K, et al. Central and peripheral des-acyl ghrelin regulates body temperature in rats[J]. Biochem Biophys Res Commun, 2013, 430 (1): 278-283.
|
| 93 |
Inoue Y, Hayashi Y, Kangawa K, et al. Des-acyl ghrelin prevents heatstroke-like symptoms in rats exposed to high temperature and high humidity[J]. Neurosci Lett, 2016 (615): 28-32.
|
| 94 |
Tseng LS, Chen SH, Lin MT, et al. Umbilical cord blood-derived stem cells improve heat tolerance and hypothalamic damage in heat stressed mice[J]. Biomed Res Int, 2014: 685683.
|
| 95 |
Umemura Y, Ogura H, Matsuura H, et al. Bone marrow-derived mononuclear cell therapy can attenuate systemic inflammation in rat heatstroke[J]. Scand J Trauma Resusc Emerg Med, 2018, 26 (1): 97.
|
| 96 |
Wan Y, Sun SS, Fu HY, et al. Adjuvant rhubarb alleviates organs dysfunction and inhibits inflammation in heat stroke[J]. Exp Ther Med, 2018, 16 (2): 1493-1498.
|
| 97 |
Jin H, Chen Y, Ding C, et al. Microcirculatory disorders and protective role of xuebijing in severe heat stroke[J]. Sci Rep, 2018, 8 (1): 4553.
|
| 98 |
Chen GD, Fan H, Zhu JH. Salidroside pretreatment protects against myocardial injury induced by heat stroke in mice[J]. J Int Med Res, 2019, 47 (10): 5229-5238.
|