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中华危重症医学杂志(电子版) ›› 2023, Vol. 16 ›› Issue (04) : 331 -334. doi: 10.3877/cma.j.issn.1674-6880.2023.04.012

综述

驱动压在体外膜肺氧合治疗急性呼吸窘迫综合征患者肺保护通气策略中的研究进展
轩晨昊, 许红阳()   
  1. 214023 江苏无锡,南京医科大学附属无锡人民医院重症医学科
  • 收稿日期:2022-10-18 出版日期:2023-08-31
  • 通信作者: 许红阳
  • 基金资助:
    太湖人才计划之高端专家团队项目(2021THRC-TD-ZZYXK-2021)
  • Received:2022-10-18 Published:2023-08-31
引用本文:

轩晨昊, 许红阳. 驱动压在体外膜肺氧合治疗急性呼吸窘迫综合征患者肺保护通气策略中的研究进展[J]. 中华危重症医学杂志(电子版), 2023, 16(04): 331-334.

急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)是重症学科面临的"大敌"之一[1],由直接损伤和间接损伤引起[2],采用柏林诊断定义[3]。ARDS患者占所有重症患者的10.4%,重度ARDS占23.4%,且重度ARDS患者住院病死率高达46.1%[3-4]。近年来随着体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)技术的进一步成熟,重度ARDS患者接受ECMO治疗的比例迅速增加[5],尤其是静脉-静脉体外膜肺氧合(veno-venous extracorporeal membrane oxygenation,VV-ECMO)在改善重度ARDS患者肺功能和提供超保护性通气方面的作用日益得到重视[6]。驱动压(driving pressure,DP)是呼吸系统扩张的直接动力,无自主呼吸时,DP=平台压-呼气末正压,其在ARDS患者肺保护通气中的作用显著。而在ECMO治疗期间,机械通气呼吸参数的设定还未有明确定论,现就DP在应用ECMO治疗的ARDS患者中的研究进展进行论述。

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