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中华危重症医学杂志(电子版) ›› 2019, Vol. 12 ›› Issue (02) : 73 -79. doi: 10.3877/cma.j.issn.1674-6880.2019.02.001

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肠道微生态制剂老年人临床应用中国专家共识(2019)
中华医学会老年医学分会, 《中华老年医学杂志》编辑委员会   
  • 收稿日期:2019-01-28 出版日期:2019-04-01

Chinese expert consensus on clinical application of intestinal microecological agent in the elderly

Chinese Geriatrics Society, Editorial Board of Chinese Journal of Geriatrics   

  • Received:2019-01-28 Published:2019-04-01
引用本文:

中华医学会老年医学分会, 《中华老年医学杂志》编辑委员会. 肠道微生态制剂老年人临床应用中国专家共识(2019)[J/OL]. 中华危重症医学杂志(电子版), 2019, 12(02): 73-79.

Chinese Geriatrics Society, Editorial Board of Chinese Journal of Geriatrics. Chinese expert consensus on clinical application of intestinal microecological agent in the elderly[J/OL]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2019, 12(02): 73-79.

表1 已批准上市的肠道微生态活菌制剂(2015年中国药典三部)
制品名称 细菌种类 上市时间 含量
双歧杆菌活菌胶囊 青春型双歧杆菌 1996 0.5 × 108
双歧杆菌活菌散 青春型双歧杆菌 2004 1 × 108
杆菌三联活菌胶囊 长型双歧杆菌 1995 ≥ 1 × 107
? 嗜酸乳杆菌 ? ?
? 粪肠球菌 ? ?
双歧杆菌三联活菌散 长型双歧杆菌 1997 ≥ 1.0 × 107
? 嗜酸乳杆菌 ? ?
? 粪肠球菌 ? ?
双歧杆菌乳杆菌三联活菌片 长型双歧杆菌 1998 ≥ 0.5 × 107
? 保加利亚乳杆菌 ? ?
? 嗜热链球菌 ? ?
地衣芽孢杆菌活菌胶囊 地衣芽孢杆菌 1995 2.5 × 108
? ? 2008 2.5 × 108
? ? 2015 5 × 108
地衣芽孢杆菌活菌颗粒 地衣芽孢杆菌 2007 5 × 108
? ? 2014 2.5 × 108
蜡样芽孢杆菌活菌胶囊 蜡样芽孢杆菌 1998 ≥ 2.0 × 108
蜡样芽孢杆菌活菌片 蜡样芽孢杆菌 1997 ≥ 2.0 × 108
? ? 2002 ≥ 4.0 × 108
双歧杆菌四联活菌片 婴儿双歧杆菌 2006 ≥ 1.5 × 106
? 嗜酸乳杆菌 ? ?
? 粪肠球菌 ? ?
? 蜡样芽孢杆菌 ? ?
酪酸梭菌活菌胶囊 酪酸梭状芽孢杆菌 2004 ≥ 5 × 107
? ? 2004 ≥ 1.5 × 107
酪酸梭菌活菌散 酪酸梭状芽孢杆菌 2004 ≥ 1.5 × 107
? ? 2014 1 × 107
酪酸梭菌活菌片 酪酸梭状芽孢杆菌 2004 ≥ 1.5 × 107
? ? 2014 1 × 107
凝结芽孢杆菌活菌片 凝结芽孢杆菌 2005 ≥ 5.0 × 107
酪酸梭菌二联活菌胶囊 酪酸梭状芽孢杆菌 2002 ≥ 1 × 107
? 婴儿型双歧杆菌 ? ?
酪酸梭菌二联活菌散 酪酸梭状芽孢杆菌 2002 ≥ 1 × 107
? 婴儿型双歧杆菌 ? ?
枯草杆菌活菌胶囊 枯草芽孢杆菌 2003 ≥ 2.5 × 107
枯草杆菌肠球菌二联活菌多维颗粒 枯草芽孢杆菌 2010 1.5 × 108
? 屎肠球菌 ? ?
枯草杆菌肠球菌二联活菌胶囊 枯草芽孢杆菌 2003 5.0 × 108
? 屎肠球菌 ? ?
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