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中华危重症医学杂志(电子版) ›› 2016, Vol. 09 ›› Issue (06) : 384 -388. doi: 10.3877/cma.j.issn.1674-6880.2016.06.006

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论著

脉冲和组织多普勒测量重度子痫前期患者右室心肌做功指数的临床对比研究
寿列军1, 解左平1,(), 谭乳燕1, 谢乐燕1, 袁华1, 金社红1, 周佳梅1, 汪惠琴2, 李红梅2   
  1. 1. 312000 浙江绍兴,绍兴市妇幼保健院超声科
    2. 312000 浙江绍兴,绍兴市妇幼保健院产科
  • 收稿日期:2016-03-16 出版日期:2016-12-01
  • 通信作者: 解左平
  • 基金资助:
    浙江省公益性技术应用研究计划项目(2015C33296); 绍兴市公益性技术应用研究计划项目(2014B70060)

Comparative study of right ventricular myocardial performance index in patients with severe preeclampsia by pulse doppler and tissue doppler

Liejun Shou1, Zuoping Xie1,(), Ruyan Tan1, Leyan Xie1, Hua Yuan1, Shehong Jin1, Jiamei Zhou1, Huiqin Wang2, Hongmei Li2   

  1. 1. Department of Ultrasound, Shaoxing Women & Children's Hospital, Shaoxing 312000, China
    2. Department of Obstetrics, Shaoxing Women & Children's Hospital, Shaoxing 312000, China
  • Received:2016-03-16 Published:2016-12-01
  • Corresponding author: Zuoping Xie
  • About author:
    Corresponding author: Xie Zuoping, Email:
引用本文:

寿列军, 解左平, 谭乳燕, 谢乐燕, 袁华, 金社红, 周佳梅, 汪惠琴, 李红梅. 脉冲和组织多普勒测量重度子痫前期患者右室心肌做功指数的临床对比研究[J]. 中华危重症医学杂志(电子版), 2016, 09(06): 384-388.

Liejun Shou, Zuoping Xie, Ruyan Tan, Leyan Xie, Hua Yuan, Shehong Jin, Jiamei Zhou, Huiqin Wang, Hongmei Li. Comparative study of right ventricular myocardial performance index in patients with severe preeclampsia by pulse doppler and tissue doppler[J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2016, 09(06): 384-388.

目的

应用脉冲多普勒和组织多普勒两种方法测量重度子痫前期患者右室心肌做功指数(Tei指数),探讨Tei指数评价右心功能的可行性。

方法

回顾性分析2013年10月至2015年9月在绍兴市妇幼保健院住院分娩的135例孕妇,其中重度子痫前期患者(观察组)55例和血压正常孕妇(对照组)80例。测定两组孕妇的一般临床资料、右室射血分数(RVEF)、三尖瓣瓣口舒张早期E波峰值流速与舒张晚期A波峰值流速之比(E/A)等。采用脉冲多普勒法(Tei1)和组织多普勒法(Tei2)测量右室Tei指数,并将两组孕妇的Tei指数合并后,采用Pearson相关分析比较两种Tei测量方法的相关性。

结果

观察组孕妇心脏收缩压和舒张压较对照组均有显著升高[(170 ± 7)mmHg vs.(108 ± 12)mmHg、(117 ± 6)mmHg vs.(72 ± 8)mmHg,t = 37.390、36.803,P均< 0.05];而RVEF与E/A比较差异均无统计学意义(P均> 0.05)。观察组右室Tei1和Tei2指数较对照组均显著增高[(0.58 ± 0.11)vs.(0.35 ± 0.12)、(0.60 ± 0.12)vs.(0.38 ± 0.11),t = 11.809、11.256,P均< 0.05]。同时,将对照组和观察组合并后,Tei1与Tei2指数比较差异无统计学意义[(0.45 ± 0.16)vs.(0.47 ± 0.16),t = 1.212,P = 0.227],且两指数呈正相关(r = 0.908,P< 0.001)。

结论

Tei指数可以准确反映重度子痫前期患者右心整体功能;运用组织多普勒法和脉冲多普勒法测量右室Tei指数比较无明显差异,并具有高度的相关性。

Objective

To investigate the right ventricular myocardial performance index (Tei index) in patients with severe preeclampsia by applying pulse Doppler and tissue Doppler, and to explore the feasibility of Tei index in the evaluation of right ventricular function.

Methods

One hundred and thirty-five parturients admitted to Shaoxing Women & Children's Hospital from October 2013 to September 2015 were enrolled in this retrospective study. They were divided into the observation group (55 cases with severe preeclampsia) and control group (80 cases with normotension). These two groups were analyzed with the general clinical data, right ventricular ejection fraction (RVEF), the ratio of tricuspid valve diastolic early E wave peak velocity and diastolic late A wave peak velocity (E/A), etc. In addition, the pulse Doppler (Tei1) and tissue Doppler methods (Tei2) measured the right ventricular Tei index for all parturients. The method of Pearson correlation analysis investigated the correlation between two Tei index measurements, after the combination of Tei indexes in two group parturients.

Results

The systolic and diastolic blood pressures in the observation group were significantly higher than those in the control group [(170 ± 7) mmHg vs. (108 ± 12) mmHg, (117 ± 6) mmHg vs. (72 ± 8) mmHg; t = 37.390, 36.803; all P< 0.05]. There were no statistically significant differences between the two groups in RVEF and E/A (all P > 0.05). The right ventricular Tei1 index and Tei2 index in the observation group were significantly higher than those in the control group [(0.58 ± 0.11) vs. (0.35 ± 0.12), (0.60 ± 0.12) vs. (0.38 ± 0.11); t = 11.809, 11.256; all P< 0.05]. After the combination of control and observation groups, there was no statistically significant difference between Tei1 index and Tei2 index [(0.45 ± 0.16) vs. (0.47 ± 0.16), t = 1.212, P = 0.227], and these two indices were positively correlated (r = 0.908, P< 0.001).

Conclusions

Tei index can accurately reflect the right ventricular function in patients with severe preeclampsia. The measurements of the right ventricular Tei index by using tissue Doppler and pulse Doppler had no significant difference, but a high degree of correlation.

图1 脉冲多普勒和组织多普勒下心脏超声图。注:a图为心尖四腔切面脉冲多普勒显示的三尖瓣口血流图;b图为大动脉短轴切面脉冲多普勒显示的肺动脉瓣口血流图;c图为心尖四腔切面组织多普勒显示的右室心肌运动频谱
表1 两组孕妇一般临床资料的比较(±s
表2 两组孕妇心功能参数的比较(±s
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