切换至 "中华医学电子期刊资源库"

中华危重症医学杂志(电子版) ›› 2021, Vol. 14 ›› Issue (06) : 507 -511. doi: 10.3877/cma.j.issn.1674-6880.2021.06.015

综述

补阳还五汤促缺血性脑卒中后血管生成机制的研究进展
张铁松1, 黄思聪1, 潘剑威1,()   
  1. 1. 310003 杭州,浙江大学医学院附属第一医院神经外科
  • 收稿日期:2020-05-19 出版日期:2021-12-31
  • 通信作者: 潘剑威
  • 基金资助:
    浙江省中医药管理局科学研究基金项目(2018ZB070)
  • Received:2020-05-19 Published:2021-12-31
引用本文:

张铁松, 黄思聪, 潘剑威. 补阳还五汤促缺血性脑卒中后血管生成机制的研究进展[J]. 中华危重症医学杂志(电子版), 2021, 14(06): 507-511.

1
Wang Y, Cui L, Ji X, et al. The China National Stro-ke Registry for patients with acute cerebrovascular events: design, rationale, and baseline patient characteristics[J]. Int J Stroke, 2011, 6 (4): 355-361.
2
谭颗,钱德才,邓磊. 静脉溶栓桥接血管内治疗急性缺血性脑卒中患者41例分析[J/CD]. 中华危重症医学杂志(电子版)201912(6):409-412.
3
Tian Y, Di Y, Zhang J, et al. Angiogenic gene profil-es in laser-microdissected microvessels and neurons from ischemic penumbra of rat brain[J]. J Mol Neurosci, 2019, 67 (4): 643-653.
4
Krupinski J, Kaluza J, Kumar P, et al. Role of angio-genesis in patients with cerebral ischemic stroke[J]. Stroke, 1994, 25 (9): 1794-1798.
5
Wu X, Li Y, Liu H, et al. Microvessel changes in the gerbil hippocampus after cerebral ischemia and reperfusion by Buyang Huanwu decoction pretreatment[J]. Neural Regen Res, 2011, 6 (9): 656-660.
6
尹育华,吴晓光. 补阳还五汤预处理对脑缺血再灌注损伤沙鼠VEGF和Ang-1表达的影响[J]. 临床和实验医学杂志201211(7):487-488,491.
7
Ren L, Wei C, Li K, et al. LncRNA MALAT1 up-reg-ulates VEGF-A and ANGPT2 to promote angiogenesis in brain microvascular endothelial cells against oxygen-glucose deprivation via targetting miR-145[J]. Biosci Rep, 2019, 39 (3): BSR20180226.
8
Ping S, Qiu X, Kyle M, et al. Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL[J]. Neurobiol Dis, 2019 (132): 104561.
9
Zheng XW, Shan CS, Xu QQ, et al. Buyang Huanwu decoction targets SIRT1 / VEGF pathway to promote angiogenesis after cerebral ischemia / reperfusion injury[J]. Front Neurosci, 2018 (12): 911.
10
Kudo H, Takeichi O, Hatori K, et al. A potential role for the silent information regulator 2 homologue 1 (SIRT1) in periapical periodontitis[J]. Int Endod J, 2018, 51 (7): 747-757.
11
Zhang H, He S, Spee C, et al. SIRT1 mediated inhibition of VEGF / VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization[J]. Cytokine, 2015, 76 (2): 549-552.
12
Zhang YK, Han XY, Che ZY. Effects of buyang huanwu tang combined with bone marrow mesenchymal stem cell transplantation on the expression of VEGF and Ki-67 in the brain tissue of the cerebral ischemia-reperfusion model rat[J]. J Tradit Chin Med, 2010, 30 (4): 278-282.
13
胡辉,储利胜,孙斯琪,等. 补阳还五汤上调miRNA-210表达促进人脑微血管内皮细胞血管生成[J]. 中国中西医结合杂志201838(2):227-231.
14
Testini C, Smith RO, Jin Y, et al. Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2[J]. EMBO Rep, 2019, 20 (11): e47845.
15
Wen N, Guo B, Zheng H, et al. Bromodomain inhibi-tor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF / PI3K / AKT signaling pathway[J]. Int J Oncol, 2019, 55 (4): 879-895.
16
Yang J, Gao F, Zhang Y, et al. Buyang Huanwu Decoction (BYHWD) enhances angiogenic effect of mesenchymal stem cell by upregulating VEGF expression after focal cerebral ischemia[J]. J Mol Neurosci, 2015, 56 (4): 898-906.
17
Cui HJ, Yang AL, Zhou HJ, et al. Buyang huanwu decoction promotes angiogenesis via vascular endothelial growth factor receptor-2 activation through the PI3K / Akt pathway in a mouse model of intracerebral hemorrhage[J]. BMC Complement Altern Med, 2015 (15): 91.
18
Witzenbichler B, Maisonpierre PC, Jones P, et al. Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2[J]. J Biol Chem, 1998, 273 (29): 18514-18521.
19
Yun JH, Han MH, Jeong HS, et al. Angiopoietin 1 attenuates interleukin-6-induced endothelial cell permeability through SHP-1[J]. Biochem Biophys Res Commun, 2019, 518 (2): 286-293.
20
Hanahan D. Signaling vascular morphogenesis and maintenance[J]. Science, 1997, 277 (5322): 48-50.
21
Shen J, Zhu Y, Yu H, et al. Buyang Huanwu decoction increases angiopoietin-1 expression and promotes angiogenesis and functional outcome after focal cerebral ischemia[J]. J Zhejiang Univ Sci B, 2014, 15 (3): 272-280.
22
周颖. 补阳还五汤通过Connexin43介导大鼠脑缺血再灌注后血管新生[D]. 广州:广州中医药大学,2019.
23
周华军,唐涛,钟建华,等. 补阳还五汤对脑出血大鼠脑内促血管生成素-1及其受体mRNA表达的影响[J]. 中国中西医结合杂志200828(4):343-347.
24
陈晨. 补阳还五汤对急性脑梗死患者血管内皮生长因子、血管生成素-2及神经功能影响的研究[J]. 陕西中医201940(1):28-30.
25
Jiang Q, Ding S, Wu J, et al. Norepinephrine stimula-tes mobilization of endothelial progenitor cells after limb ischemia[J]. PLoS One, 2014, 9 (7): e101774.
26
Li L, Liu H, Xu C, et al. VEGF promotes endothelial progenitor cell differentiation and vascular repair through connexin 43[J]. Stem Cell Res Ther, 2017, 8 (1): 237.
27
Zippo A, De Robertis A, Bardelli M, et al. Identifica-tion of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro[J]. Blood, 2004, 103 (12): 4536-4544.
28
Yu G, Li S, Liu P, et al. LncRNA TUG1 functions as a ceRNA for miR-6321 to promote endothelial progenitor cell migration and differentiation[J]. Exp Cell Res, 2020, 388 (1): 111839.
29
吴燕,杨俊杰,叶澄健,等. 补阳还五汤治疗糖尿病下肢血管病变32例疗效分析[J]. 新中医201547(7):97-99.
30
刘锟,李坤,董国华,等. 补阳还五汤对外周血内皮祖细胞数量和功能的影响[J]. 中国组织工程研究与临床康复201115(6):1044-1049.
31
张伟,贺冰,李亮,等. 补阳还五汤促进内皮祖细胞修复损伤血管内皮[J]. 中国病理生理杂志201733(11):1969-1974.
32
贺冰,刘晓丹,李亮,等. 整合素αvβ3介导EPCs修复损伤血管内皮及补阳还五汤的干预作用[J]. 湖南中医药大学学报201838(3):261-265.
33
佘颜,王宇红,邵乐,等. 补阳还五汤精简方对大鼠脑缺血后血管新生及Nrf2 / HO-1信号途径的影响[J]. 中国药理学通报201632(1):123-127,128.
34
齐勇,唐涛,罗杰坤,等. 益气活血法对脑出血大鼠脑内TSP-1、TSP-2及其受体CD36表达的影响[J]. 中国老年学杂志200727(10):913-916.
35
沈建. 补阳还五汤抗脑缺血作用及促血管新生的机制研究[D]. 杭州:浙江大学,2014.
No related articles found!
阅读次数
全文


摘要