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中华危重症医学杂志(电子版) ›› 2018, Vol. 11 ›› Issue (02) : 120 -123. doi: 10.3877/cma.j.issn.1674-6880.2018.02.010

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唑来膦酸与阿仑膦酸钠对老年骨质疏松症骨密度和骨代谢指标的影响
蒋婧瑾1, 徐丽倩1, 周文静1, 杨云梅1,()   
  1. 1. 310003 杭州,浙江大学医学院附属第一医院老年病科
  • 收稿日期:2017-11-20 出版日期:2018-04-01
  • 通信作者: 杨云梅
  • 基金资助:
    国家临床重点专科建设项目(国卫办医函[2013]544号); 浙江省医药卫生科技项目(2013KYB119、2014KYB095)
  • Received:2017-11-20 Published:2018-04-01
引用本文:

蒋婧瑾, 徐丽倩, 周文静, 杨云梅. 唑来膦酸与阿仑膦酸钠对老年骨质疏松症骨密度和骨代谢指标的影响[J]. 中华危重症医学杂志(电子版), 2018, 11(02): 120-123.

表1 三组老年骨质疏松患者治疗前骨密度、骨代谢指标的比较(±s
表2 三组老年骨质疏松患者治疗后骨密度、骨代谢指标的比较(±s
[1]
Cauley JA, Chalhoub D, Kassem AM, et al. Geographic and ethnic disparities in osteoporotic fractures[J]. Nat Rev Endocrinol, 2014, 10 (6): 338-351.
[2]
贺丽英,孙蕴,要文娟,等. 2010-2016年中国老年人骨质疏松症患病率meta分析[J].中国骨质疏松杂志,2016,22(12):1590-1596.
[3]
陈良,陈巧杰,武少坤,等.老年骨质疏松性踝关节骨折手术治疗41例分析[J/CD].中华危重症医学杂志(电子版),2015,8(2):120-122.
[4]
陈叶海,杨俊涛,黄明伟,等.编织网袋在伴有后壁破裂脊柱骨质疏松性骨折中的应用[J/CD].中华危重症医学杂志(电子版)2016,9(5):297-299.
[5]
李江伟,叶川,孙立.生物型与骨水泥半髋置换治疗老年股骨颈骨折的对比观察[J/CD].中华危重症医学杂志(电子版),2014,8(1):35-37.
[6]
Black DM, Cummings SR, Karpf DB, et al. Random-ised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group[J]. Lancet, 1996, 348 (9041): 1535-1541.
[7]
Lau EM, Woo J, Chan YH, et al. Alendronate prev-ents bone loss in Chinese women with osteoporosis[J]. Bone, 2000, 27 (5): 677-680.
[8]
Black DM, Delmas PD, Eastell R, et al. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis[J]. N Engl J Med, 2007, 356 (18): 1809-1822.
[9]
Lyles KW, Colón-Emeric CS, Magaziner JS, et al. Zo-ledronic acid and clinical fractures and mortality after hip fracture[J]. N Engl J Med, 2007, 357 (18): 1799-1809.
[10]
Giger EV, Castagner B, Leroux JC. Biomedical app-lications of bisphosphonates[J]. J Control Release, 2013,167 (2): 175-188.
[11]
Kanis JA, Reginster JY, Kaufman JM, et al. A re-appraisal of generic bisphosphonates in osteoporosis[J]. Osteoporos Int, 2012, 23 (1): 213-221.
[12]
Bauer DC, Schwartz A, Palermo L, et al. Fracture prediction after discontinuation of 4 to 5 years of alendronate therapy: the FLEX study[J]. JAMA Intern Med, 2014, 174 (7): 1126-1134.
[13]
Boonen S, Reginster JY, Kaufman JM, et al. Fracture risk and zoledronic acid therapy in men with osteoporosis[J]. N Engl J Med, 2012 367 (18): 1714-1723.
[14]
Orwoll ES, Miller PD, Adachi JD, et al. Efficacy and safety of a once-yearly i.v. Infusion of zoledronic acid 5 mg versus a once-weekly 70-mg oral alendronate in the treatment of male osteoporosis: a randomized, multicenter, double-blind, active-controlled study[J]. J Bone Miner Res, 2010, 25 (10): 2239-2250.
[15]
McClung M, Recker R, Miller P, et al. Intravenous zoledronic acid 5 mg in the treatment of postmenopausal women with low bone density previously treated with alendronate[J]. Bone, 2007, 41 (1): 122-128.
[16]
Hadji P, Gamerdinger D, Spieler W, et al. Rapid Onset and Sustained Efficacy (ROSE) study: results of a randomised, multicentre trial comparing the effect of zoledronic acid or alendronate on bone metabolism in postmenopausal women with low bone mass[J]. Osteoporos Int, 2012, 23 (2): 625-633.
[17]
Saag K, Lindsay R, Kriegman A, et al. A single zoledronic acid infusion reduces bone resorption markers more rapidly than weekly oral alendronate in postmenopausal women with low bone mineral density[J]. Bone, 2007, 40 (5): 1238-1243.
[18]
Tan W, Sun J, Zhou L, et al. Randomized trial comparing efficacies of zoledronate and alendronate for improving bone mineral density and inhibiting bone remodelling in women with post-menopausal osteoporosis[J]. J Clin Pharm Ther, 2016, 41 (5): 519-523.
[19]
Al-Bogami MM, Alkhorayef MA, Bystrom J, et al. Favorable therapeutic response of osteoporosis patients to treatment with intravenous zoledronate compared with oral alendronate[J]. Saudi Med J, 2015, 36 (11): 1305-1311.
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